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12-month warranty
Same day dispatch
Professionally endorsed

What Is the Vagus Nerve? A Complete Guide

A woman touching the back of her neck with both hands

Understanding what is the vagus nerve can have a significant impact on overall health and well-being. Thus, people should know its function and role. The longest nerve in the body is the vagus. It runs from the brainstem to the abdomen. Moreover, it is responsible for regulating various bodily functions. This includes digestion, heart rate, and mood. The diseases that affect the vagus nerve are gastrointestinal tract disorders, diabetic neuropathies, and depression.

The vagus nerve helps many abdominal organs, such as the stomach, small intestine, and liver. Also, it plays a vital role in controlling the digestive processes. Specifically, it sends signals to the digestive tract muscles that help break down food, absorb nutrients, and move food through the gastrointestinal tract. Hence, maintaining the proper function of this nerve is crucial. The article will present the vagus nerve, including its anatomy and the effects of stimulation.

What Is the Vagus Nerve?

The answer to what is the vagus nerve is that it is a prominent part of the parasympathetic nervous system of the body. It regulates essential bodily functions and extends from the brainstem to the abdomen. This cranial nerve passes through organs like the heart, lungs, and digestive system, influencing their relaxation response. Additionally, it plays a role in the communication between the brain and the gut, known as the gut-brain axis, which affects mental health and overall well-being.

People often refer to the vagus nerve as the wandering nerve due to its far-reaching connections. This extensive network allows it to play a central role in regulating different body functions. Moreover, it promotes restorative processes since it controls the parasympathetic nervous system. Consequently, it helps counteract the effects of a fight-or-flight response.

Furthermore, the vagus nerve stimulates the immune response by releasing inflammatory molecules and neural signals. This allows it to help with digestion, food absorption, and nutrient transportation. Other functions of the nerve include controlling heart rate, blood pressure, facial expression, sweating, and vocalisation.

Main Functions

  • Regulates heart rate – The vagus nerve controls the electrical conduction of the heart and reduces the heart rate when necessary.
  • Manages digestion – It signals the release of stomach acid and digestive enzymes. Also, it controls the movement of food through the gastrointestinal tract.
  • Controls breathing – This nerve regulates the respiratory system, helping to control the rate and depth of breathing.
  • Modulates inflammation – It has anti-inflammatory effects. Thus, it promotes overall immune health.
  • Regulates mood and stress response – The cranial nerve plays a role in influencing emotions and helping to keep the body in a calm and balanced state.

A woman touching her abdomen due to pain

What Is the Vagus Nerve: Basic Anatomy

People interested in learning what is the vagus nerve should know that it is the tenth and the longest cranial nerve in the body. It originates in the medulla oblongata of the brainstem and extends down through the neck, chest, and abdomen. This nerve is a component of the parasympathetic nervous system, which controls involuntary bodily functions.

The auricular branch and the vagal trunk run along the outside of the esophagus. This provides sensation in the organs of the neck and chest. Moreover, the left vagus nerve regulates the parasympathetic nervous system, which helps the body to rest and relax. On the other hand, the right vagus nerve regulates the sympathetic nervous system, which helps to prepare the body for fight or flight responses.

The vagus nerve includes two main components: the superior and inferior vagal ganglia. These ganglia contain cell bodies of nerve fibres and are responsible for relaying signals to and from the brain. The vagus nerve also has afferent (sensory) and efferent (motor) fibres, allowing it to transmit information from the organs to the brain and vice versa.

Diseases Affecting It

One common disease that affects the tenth cranial nerve is vagus nerve disorder. It can cause symptoms such as difficulty swallowing, a hoarse voice, and changes in heart rate. Another one is gastroparesis, a condition in which the stomach takes too long to empty its contents. The symptoms are nausea and vomiting.

Other diseases include Gastroesophageal Reflux Disease (GERD) and Irritable Bowel Syndrome (IBS). Also, diabetes can cause damage to the vagus nerve. Furthermore, there can be depression and bipolar disorder. This leads to decreased vagal tone, which is necessary for the proper functioning of the autonomic nervous system.

A TENS machine with essential information about it

What Is the Vagus Nerve: Effects of Stimulation

After understanding what is the vagus nerve, people should know the effects of stimulation on it. When this nerve is stimulated, it can help reduce heart rate and blood pressure. This can be beneficial for managing stress and anxiety and may also have positive effects on depressive disorders. In addition, stimulating the nerve can promote relaxation and decrease inflammation, helping people with chronic pain.

Moreover, vagus nerve stimulation can improve digestion and reduce symptoms of IBS. By regulating the function of the digestive organs, it may alleviate discomfort and improve overall gut health. Additionally, vagus nerve stimulation may positively impact memory and brain activity. Hence, it is an area of interest for the potential treatment of mental conditions.

Stimulating the tenth cranial nerve through techniques such as deep breathing or electrical stimulation can have various positive effects on physical and mental health. However, it is important to note that the effects of vagal nerve stimulation can vary from person to person. Thus, it is best to discuss possible treatments with a medical professional before trying any new techniques.

TENS Therapy

Transcutaneous Electrical Nerve Stimulation or TENS therapy can relieve pain for diseases affecting the vagus nerve. It uses a portable, battery-operated device to send low-voltage electrical currents to the affected area. This non-invasive treatment option targets nerve fibres. As a result, it modulates pain signals, promotes healing, and increases blood flow.

TENS therapy works by stimulating the nerves through the skin. This can help regulate the activity of the nerve and improve symptoms related to inflammatory conditions and other pain conditions. This approach can also enhance the production of endorphins, the natural painkillers of the body, to manage discomfort and improve overall well-being.


Answering what is the vagus nerve is simple. It is the tenth and longest nerve in the body. In addition, it extends from the brainstem to the abdomen, branching out to various organs along the way. This nerve plays a crucial role in regulating blood pressure, digestion, and inflammation. People can have diseases like gastrointestinal tract disorders, cardiovascular diseases, and diabetes. Moreover, it affects the voice box, which leads to difficulty swallowing and loss of voice.

The beneficial effects of vagus nerve stimulation, such as through TENS therapy, include pain relief, better mood, and improved blood circulation. Also, it manages many pain conditions like fibromyalgia and arthritis. It is generally safe to use because it utilises mild electric currents. There is much clinical evidence surrounding the effectiveness of electrical stimulation. Therefore, it does not damage internal organs or cause adverse side effects. However, individuals should follow the safety guidelines to avoid involuntary muscle contractions.

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